アト（10-18）モルオーダーの極微量物質の分離・検出に成功。 頂点が見えた！
Batch-type Chemiluminescence Detection Cell for Sensitization and Simplification of Capillary Electrophoresis: Kazuhiko Tsukagoshi, Takeshi Nakamura, and Riichiro Nakajima, Analytical Chemistry, 74, 4109-4116 (2002).
標識を必要としない新しい生体成分の微量検出法を開発。 科学の不思議！
Direct Detection of Biomolecules in a Capillary Electrophoresis-Chemiluminescence Detection System: Kazuhiko Tsukagoshi, Koji Nakahama, and Riichiro Nakajima, Analytical Chemistry, 76, 4410-4415 (2004).
人血清中から癌タンパク質をわずか１分で分離、検出。 マイクロチップを使って世界初！
Development of a Micro-Total Analysis System Incorporating Chemiluminescence Detection and Application to Detection of Cancer Markers: Kazuhiko Tsukagoshi, Naoya Jinno, Riichiro Nakajima, Analytical Chemistry, 77, 1684-1688 (2005).
固定相がなくてもクロマトグラフィーで分離ができる。 既存概念からの脱却！
Analytical Conditions and Separation performance of Capillary Chromatography Based on the Tube Radical Distribution of Aqueous -Organic Mixture Carrier Solvents under laminar–Flow Conditions; Naoya Jinno, Mari Murakami, Masahiko Hashimoto, and Kazuhiko Tsukagoshi, Analytical Sciences, 26, 737-742 (2010).
微小領域の不思議な流れ。 相分離混相流の発見！
Fluorescence Observation Supporting Capillary Chromatography Based on Tube Radial Distribution of Carrier Solvents under Laminar Flow Conditions; Naoya Jinno, Mari Murakami, Kiyoshi Mizohata, Masahiko Hashimoto, and Kazuhiko Tsukagoshi, Analyst, 136, 927-932 (2011).
管径方向分配現象の発生メカニズムの解明。 Most Cited Paper Award受賞！
Tube Radial Distribution Phenomenon of Ternary Mixed Solvents in a Microspace under Laminar Flow Conditions; Mari Murakami, Naoya Jinno, Masahiko Hashimoto, and Kazuhiko Tsukagoshi, Analytical Sciences, 27, 793-798 (2011).
化学工学、流体工学、分析化学の融合に、２次モーメント微分方程式から挑戦。 新学術領域の開拓！
Study of Outer Phases in Capillary Chromatography, Based on Tube Radial Distribution of Carrier Solvents under Laminar Flow Conditions; Naoya Jinno, Mari Murakami, Kiyoshi Mizohata, Masahiko Hashimoto, and Kazuhiko Tsukagoshi, Journal of Liquid Chromatography & Related Technologies, 35, 1750–1766 (2012).
固定相を使わず、流すだけで、ついに光学異性体までもが分離。 無限の可能性を示唆！
Separation of Dansyl-DL-Amino Acids by Open Tubular Capillary Chromatography Based on Tube Radial Distribution Phenomenon of the Ternary Mixed Carrier Solvents; Yudai Kudo, Hyo Kan, Naoya Jinno, Masahiko Hashimoto, and Kazuhiko Tsukagoshi, Analytical Methods, 4, 906-912 (2012).
相分離混相流を粘性散逸法則と線形安定性解析から考察。 学術的体系化へ大きく前進！
Consideration of Inner and Outer Phase Configuration in Tube Radial Distribution Phenomenon Based on Viscous Dissipation in a Microfluidic Flow Using Various Types of Mixed Solvent Solutions; Satoshi Fujinaga, Masahiko Hashimoto, Kazuhiko Tsukagoshi, and Jiro Mizushima, Analytical Sciences, 32, 455-461 (2016).
市販のHPLC装置で分離カラムを使わずに分離ができた。 HPLCの概念を覆す！
Tube Radial Distribution Chromatography System Developed by Combining Commercially Available HPLC System and Open-Tubular Capillary Tube as Separation Column; Kento Yamada, Hyo Kan, and Kazuhiko Tsukagoshi, Talanta, 183, 89-93 (2018).
「Inverted Flow」の発見と「Response Microfluidic Analysis」の提案。マイクロ流体を新たな学術領域へといざなう！（2021年FIA論文賞 (FIA Award for Original Papers)受賞）
Microfluidic Inverted Flow of Ternary Water/Hydrophilic/Hydrophobic Organic Solvent Solution in a Y-Type Microchannel and a Proposal of the Response Microfluidic Analysis through the Experiment; Bun Yamawaki, Ryuki Mori, Kazuhiko Tsukagoshi, Katsumi Tsuchiya, Kenichi Yamashita, and Masaharu Murata, Analytical Sciences, 35, 249-256 (2019).
HPLC装置で分離カラムを使わず、試料の連続注入・分離・検出ができた。 HPLCとFIAを融合する概念を提案！
Consecutive Sample Injection analysis in Tube Radial Distribution Chromatography; Yusaku Takahashi, Kazushi Nishimura, Kazuhiko Tsukagoshi, Katsumi Tsuchiya, Ken Hirota, Kenichi Yamashita, and Masaharu Murata, Analytical Sciences, 37, 1373-1377 (2021).
相分離混相流を溶離液として分離カラムを備えた市販HPLC装置に初めて適用。新規HPLC分離モードの開発！（Hot Article Award Analytical Sciences (July 15, 2022)を受賞）
Novel Separation Mode of HPLC Based on Phase-Separation Multiphase Flow; Kosei Horikawa, Satoru Kinoshita, Katsumi Tsuchiya, and Kazuhiko Tsukagoshi, Analytical Sciences, 38, 931-933 (2022).
