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発表論文

Selected Papers



S. Nishimura, N. Higashi, T. Koga,  Facile Synthesis of Multiblock Copolymers Containing Sequence-controlled Peptides and Well-defined Vinyl Polymers via Nitroxide-mediated Polymerization., Chem. Eur. J., in press (2017).



N. Higashi, A. Hirata, S. Nishimura, T. Koga,  Thermo-responsive Polymer Brushes on Glass Plate Prepared from a New Class of Amino Acid-derived Vinyl Monomers and Their Applications in Cell-sheet Engineering., Colloid. Surf. B Biointerface, 159, 39-46 (2017).



N. Higashi, D. Sekine, T. Koga,  Temperature Induced Self-assembly of Amino Acid-derived Vinyl Block Copolymers via Dual Phase Transitions., J. Colloid. Interface Sci., 500, 341-348 (2017).


西村 慎之介・古賀 智之・東 信行,  天然アミノ酸からつくる温度応答性高分子, 化学, 72, 62-63 (2017).


T. Koga, E. Aso, N. Higashi, Novel Self-assembling Amino Acid-derived Block Copolymer with Changeable Polymer Backbone Structure, Langmuir, 32, 12378-12386 (2016).


西村 慎之介・古賀 智之・東 信行,  Coiled-coil型三分岐ペプチドの自己組織化によるナノ構造形成, 

高分子論文集, 73, 175-182 (2016). 


T. Koga, K. Mima, T. Matsumoto, N. Higashi, Amino Acid-derived Polymer with Changeable Enzyme Degradability based on pH-Induced Structural Conversion from Polyester to Polypeptide, Chem. Lett. 44, 1720-1722 (2015).


N. Higashi, R. Sonoda, T. Koga, Thermo-responsive Amino Acid-based Vinyl Polymers Showing Widely Tunable LCST/USCT Behavior in Water, RSC Advances, 5, 67652-67657 (2015).


T. Koga, K. Nakamoto, K. Odawara, T. Matsuoka, N. Higashi, Fabrication of Thermo-responsive Molecular Layers from Self-assembling Elastin-like Oligopeptides Containing Cell-binding Domain for Tissue Engineering, Polymers, 7, 134-146 (2015).


 N. Terasawa, Y. Hayashi, T. Koga, N. Higashi, K. Asaka, High Performance Polymer Actuators Based on Poly(ethylene oxide) and Single-walled Carbon Nanotubes-Ionic Liquid-based Gels, Sensors and Actuators B, 202, 382-387 (2014).


 N. Higashi, K. Yasufuku, Y. Matsuo, T. Matsumoto, T. Koga, Thermo-Responsive Multilayer Films from Ionic Polymers with Elastin- Like Peptide as Graft Chains, Colloid Interface Sci. Commun., 1, 50-53 (2014). 


神渡 壮一・古賀 智之・東 信行, 両親媒性ペプチドブロックポリマーで安定化した水/トルエン・ナノエマルションを利用したナノゲルの調製、同志社大学理工学研究所報告, 55(2), 126-131 (2014).


古賀 智之, 人工ペプチドを基盤とする温度応答性ナノ材料の開発, C&I Commun. 39, 15-17, (2014).


T. Koga, S. Kamiwatari, N. Higashi, Preparation and Self-Assembly Behavior of β-Sheet Peptide-Inserted Amphiphilic Block Copolymer as a Useful Polymeric Surfactant, Langmuir, 29, 15477-15484 (2013).


N. Higashi, T. Ochiai, C. Kanazawa, T. Koga, Site-specific Adsorption of Gold Nanoparticles Coated with Thermo-responsive Peptides, Polymer J., 45, 523-528 (2013).


N. Terasawa, N. Ono, K. Mukai, T. Koga, N. Higashi, K. Asaka, High Performance Polymer Actuators Based on Multi-walled Carbon Nanotubes that Surpass the Performance of Those Containing Single-walled Carbon Nanotubes: Effects of Ionic Liquid and Composition, Sensors and Actuators B, 163 20-28 (2012).


T. Koga, Y. Teraguchi, N. Higashi, Preparation of PHEMA Copolymers Containing Cell-binding Peptides as Graft Chains and Their Cell Adhesive Properties, Trans. Mater. Res. Soc. Jpn., 37(4), 533-536 (2012).


N. Terasawa, N. Ono, K. Mukai, T. Koga, N. Higashi, K. Asaka, A Multi-walled Carbon Nanotube/Polymer Actuator that Surpasses the Performance of a Single-walled Carbon Nanotube/Polymer Actuator, Carbon, 50, 311-320 (2012).


T. Koga, M. Iimura, N. Higashi, Novel Peptide-shelled Dendrimer with Dramatically Changeable Thermo-responsive Character, Macromol. Biosci., 12, 1043-1047 (2012).


T. Koga, T. Taguchi, N. Higashi, β-Sheet Peptide-assisted Polymerization of Diacetylene at the Air-water Interface and Thermochromic Property, Polymer J., 44, 195-199 (2012). (Cover picture of this issue)


N. Terasawa, N. Ono, Y. Hayakawa, K. Mukai, T. Koga, N. Higashi, K. Asaka, Effect of Hexafluoropropylene on the Performance of Poly(vinylidene fluoride) Polymer Actuators Based on Single-walled Carbon Nanotube–Ionic Liquid Gel, Sensors and Actuators B, 160, 161-167 (2011).


古賀 智之・城 大悟・東 信行, ペプチド・ナノ薄膜の開発と機能材料への応用, IEICE Technical Report SDM&OME, 43-46 (2011).


T. Koga, M .Koike, S. Kamiwatari, N. Higashi, Rod-coil Transition-based Morphological Variation of Peptide-synthetic Hybrid Block Copolymer Assemblies in Non-aqueous Media, Chem. Lett., 40, 1244-1246 (2011).


 T. Koga, H. Matsui, T. Matsumoto, N. Higashi, Shape-specific Nanofibers via Self-assembly of Three-branched Peptide, J. Colloid. Interface Sci., 358, pp. 81-85 (2011).


古賀 智之・深見 史郎・東 信行, エラスチン類似ペプチドでポリアクリル酸をネットワーク化した二重応答性ハイドロゲル, ネットワークポリマー, 31, 278-288 (2010).


古賀 智之・西馬 千恵・東 信行, ペプチドのコンフォメーションスイッチを駆動力とする温度応答性高分子ミセル, 高分子論文集, 67, 679-685 (2010).


N. Higashi, Y. Gondo, T. Matsumoto, T. Koga, Self-Assembled Fibrous Nano-Object Generated from Coiled-Coil Polypeptide Diblock Copolymer,  Trans. Mater. Res. Soc. Jpn., 35(4), 829-832 (2010).


N. Higashi, T. Takagi, T. Koga, Layer-by-layer Fabrication of Well-packed Gold Nanoparticle Assemblies Guided by β-sheet-peptide Template, Polymer J., 42, 95-99 (2010).


M. Tanaka, S. Abiko, T. Koga, N. Koshikawa, T. Kinoshita, Aggregation Induced α-Helix/β-Sheet Transition of the Poly(ethylene glycol)-attached Peptide, Polymer J., 41, 153-156 (2009).


T. Koga, T. Watanabe, N. Higashi, Fabrication of Nucleobase-functionalized Supramolecular Nanofiber through Peptide Self-assembly, J. Nanosci. Nanotechn., 9, 584-590. (2009).


T. Koga, N. Higashi, Fabrication of Peptide-Nanoarchitectures through Molecular Self-Assembly, Bottom-up Nanofabrication: Supramolecules, Self-Assemblies, and Organized Films, Ed. K. Ariga and H. S. Nalwa, Publisher: American Scientific Publishers, 4, 241-268 (2009).


N. Higashi, T. Koga, Self-assembled Peptide Nanofibers, Adv. Polym. Sci., 219, 27-68 (2008).


T. Koga, M. Ushirogochi, N. Higashi, Regulation of Self-assembling Process of a Cationic β-Sheet Peptide by Photoisomerization of an Anionic Azobenzene Derivative., Polymer J., 39, 16-17 (2007).


T. Koga, R. Murakami, N. Higashi, Surface Modification of Peptide Nanofiber by Using Antigen-Antibody Interaction, Trans. Mater. Res. Soc. Jpn., 32(2), 371-374. (2007).


T. Koga, K. Kitamura, N. Higashi, Enzymatically Triggered Self-assembly of Poly(ethylene glycol)-attached Oligopeptide into Well-organized Nanofibers. Chem. Commun., 4897-4899 (2006). (Inside cover of this issue).


N. Higashi, A. Uchino, Y. Mizuguchi, M. Niwa, Chain Length Effects of Oligo(L-lysine)-shelled Dendrimers on Interaction with DNA. Int. J. Biol. Macromol., 38, 120-125 (2006). 


N. Higashi, T. Shosu, T. Koga, M. Niwa, T. Tanigawa, pH-Responsive, Self-assembling Nanoparticle from a Fullerene-tagged Poly(l-glutamic acid) and Its Superoxide Dismutase Mimetic Property.  J. Colloid and Interface Sci., 298, 118-123 (2006).


T. Koga, A. Nagaoka, N. Higashi, Fabrication of a Switchable Nano-surface Composed of Acidic and Basic Block Polypeptides. Colloids. Surf. A, 284/285, pp. 521-527 (2006).


T. Koga, M. Higuchi, T. Kinoshita, N. Higashi, Controlled Self-assembly of Amphiphilic Oligopeptides into Shape-specific Nanoarchitectures.  Chem. Eur. J. 12, 1360-1367 (2006).  (Cover picture of this issue).


T. Koga, M. Matsuoka, N. Higashi, Structural Control of Self-assembled Nanofibers by Artificial β-Sheet Peptides Composed of D- or L-Isomer.  J. Am. Chem. Soc. 127, 17596-17597 (2005).


M. Niwa, K. Sugamoto, T. Koga, N. Higashi, Nanostructure Formation from a Poly(glutamic acid)-based Helix-Loop-Helix Copolymer and Its Stable Encapsulation of Antitumor Reagent.  J. Biomed. Nanotech., 1, 345-351 (2005).


N. Higashi, J. Kawahara, M. Niwa, Preparation of Helical Peptide Monolayer-coated Gold Nanoparticles.  J. Colloid and Interface Sci., 288, 83-87 (2005).


M. Nakano, T. Koga, N. Higashi, Facile Synthesis of Amphiphilic Diblock Polypeptides through Ion-Complexation and Their Self-Assembling Properties in Water.   Trans. Mater. Res. Soc. Jpn., 30, 337-340 (2005).







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