Study

Research project-1

Mechanisms for chiral recognition by cyclic and noncyclic oligosaccharides

• Circular dichroism and fluorescence studies on chiral pyrene dimer in g-cyclodextrin cavity.
• Conformational enantiomerism of bilirubin and pamoic acid induced by oligosaccharides.
• Mechanisms for chiral recognition of guest having central chirality by modified cyclodextrins.
• Recognition of axial chirality and helicity by cyclic and noncyclic oligosaccharides.
• Chirality separation by capillary zone electrophoresis.
• Chiral recognition by monolayer assemblies at air-water interface and by chiral SAM on gold.
• Mechanisms for formation of molecular assemblies of water-soluble porphyrins.
• Inclusion complexes of water-soluble porphyrins and cyclodextrins and their function.
• Chiral recognition of Ru and Rh trisphenanthroline complexes by anionic cyclodextrins.
• General mechanism for chiral recognition by cyclodextrins.
• Supramolecular chemistry composed of water-soluble porphyrins and cyclodextrins.
• Myoglobin models that works in 100% aqueous solution.

Future project

• Simplest metalloenzyme model.
• Interactions of cyclodextrins and proteins.
• Preparation of hydrogels of cyclodextrin polymer.

Research project-2

Synthesis of polynuclear metal complexes as structural and functional models of polynuclear metal biosites

• Design and synthesis of dinucleating hexapyridine ligands which do not have a bridging group.
• Model compounds for sMMO
• Model compounds for oxyhemocyanin

Future project

• Studies on structural and functional models for non-heme proteins